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Faculty

Lin Zhou Associate Professor

Bio: 

Educational Background

PhD, Basic Discipline of Chinese and Western Integrative, China Pharmaceutical University (2011)

MA, Microbial resources and technologies, Nanjing Normal University (2008)

BA, Biology, Inner Mongolia University (2005)

 

Research

Research Interests

Photosensitive theranostic nanoparticle design, preparation and anticancer activity study

 

Research Projects

  1. Photodynamic therapy system based on self-illuminate nanoparticles
  2. Preparation and photodynamic therapy activity study for hypoxia tumor    based on hydrogen peroxide burst

 

Journal Articles

  1. Wang, A.; Jin, W. W.; Chen, E. Y.; Zhou, J. H.; Zhou, L.*; Wei, S. H*. Drug delivery function of carboxymethyl-beta-cyclodextrin modified upconversion nanoparticles for adamantine phthalocyanine and their NIR-triggered cancer treatment. Dalton Transactions 2016, 45, 3853-3862.
  2. Wang, A.; Gui, L.; Lu, S.; Zhou, L.*; Zhou, J. H.; Wei, S. H.* Tumor microenvironment-responsive charge reversal zinc phthalocyanines based on amino acids for photodynamic therapy. Dyes and Pigments 2016, 126, 239-250.
  3. Lu, S.; Wang, A.; Ma, Y. J.; Xuan, H. Y.; Zhao, B.; Li, X. D.; Zhou, J. H.; Zhou, L.*; Wei, S. H.* Cyclodextrin type dependent host-guest interaction mode with phthalocyanine and their influence on photodynamic activity to cancer. Carbohydrate Polymers 2016, 148, 236-242.
  4. Zhou, L.; Ge, X. F.; Zhou, J. H.*; Wei, S. H.*; Shen, J. Modulating the photo-exciting process of photosensitizer to improve in vitro phototoxicity by preparing its self-assembly nanostructures. Rsc Advances 2015, 5, 2794-2805.
  5. Zhou, L.; Ge, X. F.; Zhou, J. H.*; Wei, S. H.*; Shen, J. Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A. Chemical Communications 2015, 51, 421-424.
  6. Xie, W. L.; Wei, S. H.; Liu, J. H.; Ge, X. F.; Zhou, L.*; Zhou, J. H.*; Shen, J. Combination anticancer therapy activity studies for the complex of hypocrellin A and gallium ion. Dyes and Pigments 2014, 101, 43-50.
  7. Lu, S.; Ma, Y. J.; Xuan, H. Y.; Wang, A.; Zhao, B.; Li, X. D.; Zhou, J. H.; Lin, Y.; Zhou, L.*; Wei, S. H.* A novel assembling complex of hydrobobic phthalocyanine-cyclodextrin: preparation, characterization, molecular modeling, and in vitro activity. Rsc Advances 2014, 4, 59759-59763.
  8. Zhou, L.; Wei, S. H.; Ge, X. F.; Zhou, J. H.*; Yu, B. Y.*; Shen, J. External Heavy-Atomic Construction of Photosensitizer Nanoparticles for Enhanced in Vitro Photodynamic Therapy of Cancer. Journal of Physical Chemistry B 2012, 116, 12744-12749.
  9. Zhou, L.; Jiang, H. J.; Wei, S. H.; Ge, X. F.; Zhou, J. H.*; Shen, J. High-efficiency loading of hypocrellin B on graphene oxide for photodynamic therapy. Carbon 2012, 50, 5594-5604.
  10. Zhou, L.; Wang, W.; Tang, J.; Zhou, J. H.*; Jiang, H. J.*; Shen, J. Graphene Oxide Noncovalent Photosensitizer and Its Anticancer Activity in Vitro. Chemistry-a European Journal 2011, 17, 12084-12091.

 

 

Patents

  1. Zhou, L.; Zhou, J. H.; Wei, S. H.; Chen, X.; Wu, Q.; Song, Z. Y. Hypocrellin- transferrin complex tumor target system by photodynamic therapy. (CN105617380A)
  2. Zhou, L.; Zhou, J. H.; Wei, S. H.; Ding, Y.; Chen, E. Y. Preparation and application of GO-TiO2-Hypocrellin complex for photodynamic therapy. (CN105412925A)
  3. Zhou, L.; Zhou, J. H.; Wei, S. H.; Xie, W. L.; Xiao, M. S.; Yuan, X. X. Preparation and anticancer activity of Ga3+-hypocrellin complex. (CN104961755A)
  4. Zhou, L.; Zhou, J. H.; Wei, S. H.; Yuan, X. X.; Xiao, M. S. Upconversion NaYF4:Yb3+,Tm3+ nanoparticle-hypocrellin complex preparation and application in photodynamic therapy. (CN104826111A)
  5. Zhou, L.; Zhou, J. H.; Wei, S. H.; Yang, C.; Ma, F.; Han, L. N. Calcium phosphate nanoparticle based hydrophobic anticancer drug delivery system. (CN102886046A)
  6. Zhou, L.; Zhou, J. H.; Wei, S. H.; Yang, C.; Ma, F. A method to prepare hydrophobic photosensitizer nanoparticles. (CN102988289A)

 

 

Contact

Tel:+86-025-85891761

E-mail:zhoulin@njnu.edu.cn