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Faculty

Ping Wu Associate Professor

Research Interests: 
  • 1. High sensitive and specific detection of cancer cells at low abundance based on surface-enhancement Raman spectroscopy
  • 2. Synthesis of functional metallic nanoparticles as photothermal agents for photothermal therapy treatment of cancer cells.
Bio: 

Educational Background
PhD, Biological Physical Chemistry, Nanjing Normal University (2013)
MA, Physical Chemistry, Nanjing Normal University (2005)
BA, Chemistry Education, Nanjing Normal University (2002)

Research

Research Projects

1.     “High sensitive detection of human breast cancer cell and its multiple tumor markers based on SERS tehnique”, National Natural Science Foundation of China (No. 21405083),

2.     “Electrochemical probing for conformational structure of the proteins”, Natural Science Foundation of Jiangsu Province (BK2011779)

3.     “SERS detection of tumor markers expressed on surface of human breast cancer cells”, Natural Science Foundation of the Jiangsu Education Committee (14KJB150012)

4.     “Protein misfolding and its electrochemical characteristic”, Natural Science Foundation of the Jiangsu Education Committee (14KJB150012) 
 

Journal Articles (2012-Present)

1.     Guancao Yang, Chuanli Wu, Xiaojun Luo, Xiaoyan Liu, Yuan Gao, Ping Wu,* Chenxin Cai,* S. Scott Saavedra*, Exploring the Emissive States of Heteroatom-Doped Graphene Quantum Dots, J. phys. Chem. C, 2018, 122, 6483−6492.

2.     Xiaojun Luo, Xiaoyan Liu, Yinuo Pei, Yawen Ling, Ping Wu*, Chenxin Cai*, Leakage-free polypyrrole–Au nanostructures for combined Raman detection and photothermal cancer therapy, J. Mater. Chem. B, 2017, 5, 7949−7962.

3.     Li Chen, Guancao Yang, Ping Wu⁎, Chenxin Cai⁎, Real-time fluorescence assay of alkaline phosphatase in living cells using boron-doped graphene quantum dots as fluorophores, Biosens. Bioelectrons., 2017, 96, 294–299.

4.     Li Chen, Chuanli Wu, Pan Du, Xiaowei Feng, Ping Wu⁎, Chenxin Cai⁎, Electrolyzing synthesis of boron-doped graphene quantum dots for fluorescence determination of Fe3+ ions in water samples, Talanta, 2017, 164, 100−109.

5.     Ping Wu, Dan Deng, Jingwen Gao, Chenxin Cai*, Tubelike Gold Sphere−Attapulgite Nanocomposites with a High Photothermal Conversion Ability in the Near-Infrared Region for Enhanced Cancer Photothermal Therapy, ACS Appl. Mater. Interfaces, 2016, 8, 10243–10252.

6.     Lijuan Ji, Li Chen, Ping Wu,* Dominic F. Gervasio, Chenxin Cai*, Highly Selective Fluorescence Determination of the Hematin Level in Human Erythrocytes with No Need for Separation from Bulk Hemoglobin, Anal. Chem., 2016, 88, 3935−3944.

7.     Zhewei Cai, Fumin Li, Ping Wu,* Lijuan Ji, Hui Zhang, Chenxin Cai, Dominic F. Gervasio*, Synthesis of Nitrogen-Doped Graphene Quantum Dots at Low Temperature for Electrochemical Sensing Trinitrotoluene, Anal. Chem., 2015, 87, 11803−11811.

8.     Ping Wu,* Pan Du, Hui Zhang, Chenxin Cai*, raphyne-supported single Fe atom catalysts for CO oxidation, Phys. Chem. Chem. Phys., 2015, 17, 1441–1449.

9.     Xiaoqing Xu, Yingdan Qian, Ping Wu*, Hui Zhang, Chenxin Cai, Probing the anticancer-drug-binding-induced microenvironment alterations in subdomain IIA of human serum albumin, J. Collid. Inter. Sci., 2015, 445, 102–111.

10.   Yanchun Qiu, Dan Deng, Qianwen Deng, Ping Wu* Hui Zhang, Chenxin Cai*, Synthesis of magnetic Fe3O4–Au hybrids for sensitive SERS detection of cancer cells at low abundance, J. Mater. Chem. B, 2015, 3, 4487-4495 (cover paper).

11.   Bianjun Zhao, Ping Wu*, Hui Zhang,Chenxin Cai*, Designing activatable aptamer probes for simultaneous detection of multiple tumor-related proteins in living cancer cells, Biosens. Bioelectrons., 2015, 68, 763–770.

12.   Ping Wu, Yunqiu Tu, Yingdan Qian, Hui Zhang, Chenxin Cai, DNA strand- displacement- induced fluorescence enhancement for highly sensitive and selective assay of multiple microRNA in cancer cells, Chem. Commun., 2014, 50, 1012-1014.

13.   Ping Wu, Pan Du, Hui Zhang, Chenxin Cai, Graphdiyne as a metal-free catalyst for low-temperature CO oxidation, Phys. Chem. Chem. Phys., 2014, 16(12), 5640-5648.

14.   Yemeng Ni, Yajing Yin, Ping Wu*, Hui Zhang, Chenxin Cai*, Nitrogen/Carbon Atomic Ratio-Dependent Performances of Nitrogen-Doped Carbon-Coated Metal Oxide Nanocrystals for Anodes in Lithium-Ion Batteries, ACS Appl. Mater. Interfaces, 2014, 6, 7346−7355.

15.   Yimei Lu, Ping Wu*, Yin Yajing, Zhang Hui, Chenxin Cai*, Aptamer-functionalized graphene oxide for highly efficient loading and cancer cell-specific delivery ofantitumor drug, J. Mater. Chem. B, 2014, 2, 3849–3859.

16.   Ping Wu, Hua Zhang, Yingdan Qian, Yaojuan Hu, Hui Zhang, and Chenxin Cai,* Composition- and aspect-ratio-dependent electrocatalytic performances of one-dimensional aligned Pt–Ni nanostructures, J. Phys. Chem. C, 2013, 117(37), 19091-19100.

17.   Ping Wu, Yang Gao, Yimei Lu, Hui Zhang, and Chenxin Cai,* High specific detection and near-infrared photothermal therapy of lung cancer cells with high SERS active aptamer–silver–gold shell–core nanostructures, Analyst, 2013, 138(21), 6501-6510.

18.   Ping Wu, Pan Du, Hui Zhang and Chenxin Cai*, Microscopic effects of the bonding configuration of nitrogen-doped graphene on its reactivity toward hydrogen peroxide reduction reaction, Phys. Chem. Chem. Phys., 2013, 15(18), 6920- 6928.

19.   Yingdan Qian, Xiaoqing Xu, Qian Wang, Ping Wu,* Hui Zhang, and Chenxin Cai,* Electrochemical probing the solution pH-induced structural alterations around the heme group in myoglobin, Phys. Chem. Chem. Phys., 2013, 15(39), 16941-16948.

20.   Qian Shao, Yingdan Qian, Ping Wu*, Hui Zhang, Chenxin Cai, Graphene oxide–induced conformation changes of glucose oxidase studied by infrared spectroscopy, Colloids and Surfaces B: Biointerfaces, 2013, 109, 115-120.

21.   Yunqiu Tu, Wen Li, Ping Wu,* Hui Zhang, and Chenxin Cai*, Fluorescence quenching of graphene oxide integrating with the site-specific cleavage of the endonuclease for sensitive and selective microRNA detection, Anal. Chem., 2013, 85(4), 2536-2542.

22.   Ping Wu, Pan Du, Hui Zhang, and Chenxin Cai*, Graphyne as a promising metal-free electrocatalyst for oxygen reduction reactions in acidic fuel cells: A DFT study, J. Phys. Chem. C, 2012, 116(38), 20472-20479.

23.   Ping Wu, Yang Gao, Hui Zhang, Chenxin Cai*, Aptamer-guided silver-gold bimetallic nanostructures with highly active surface-enhanced raman scattering for specific detection and near-infrared photothermal therapy of human breast cancer cells, Anal. Chem., 2012, 84(18), 7692-7699.

24.   Ping Wu, Yingdan Qian, Pan Du, Hui Zhang, Chenxin Cai*, Facile synthesis of nitrogen-doped graphene for measuring the releasing process of hydrogen peroxide from living cells, J. Mater. Chem., 2012, 22(13), 6402-6412.

25.   Yunqiu Tu, Ping Wu*, Hui Zhang, and Chenxin Cai*, Fluorescence quenching of gold nanoparticles integrating with conformation-switched hairpin oligonucleotide probe for microRNA detection, Chem. Commun., 2012, 48(87), 10718-10720.(cover paper)

26.   Wen Li, Ping Wu*, Hui Zhang, and Chenxin Cai*, Signal amplification of graphene oxide combining with restriction endonuclease for site-specific determination of DNA methylation and assay of methyltransferase activity, Anal. Chem., 2012, 84(17), 7583-7590.

27.   Yaojuan Hu, Ping Wu*, Hui Zhang, Chenxin Cai, Synthesis of graphene-supported hollow Pt-Ni nanocatalysts for highly active electrocatalysis toward the methanol oxidation reaction, Electrochim. Acta, 2012, 85, 341-321.

28.   Wen Li, Ping Wu*, Hui Zhang, Chenxin Cai*, Catalytic signal amplification of gold nanoparticles combining with conformation-switched hairpin DNA probe for hepatitis C virus quantification, Chem. Commun., 2012, 48(63), 7877-7879.

29.   Yaojuan Hu, Qian Shao, Ping Wu*, Hui Zhang, Chenxin Cai*, Synthesis of hollow mesoporous Pt–Ni nanosphere for highly active electrocatalysis toward the methanol oxidation reaction, Electrochem. Commun., 2012, 18, 96-99.



Patents

1.     HRP-attapulgite nano-hybrids for electrochemical biosensing (ZL201110064051.7) with Chenxin Cai, Hui Zhang, and Piao Gu.

2.     Method for detection of cellular hydrogen peroxide based on HRP-attapulgite nano-hybrids (ZL201110064053.6), with Chenxin Cai, Hui Zhang, and Yunqiu Tu.

3.     SERS-active nanoparticles probes for use in assay of human breast cancer cells (ZL 201210080376.9), with Chenxin Cai, and Hui Zhang.
 

Contact

Email:wuping@njnu.edu.cn