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Faculty

Wei Han Associate Professor

Research Interests: 
  • Innovation of concepts, invention of novel reagents, reactions, catalysts and creation of new catalytic systems for highly efficient organic synthesis.
  • Design of “green” synthetic methodology and new approaches for synthesizing important bioactive compounds and organic functional molecules.
Bio: 

Educational Background:

Ph.D, Organic Chemistry, Ludwig Maximilian University of Munich, Germany (2008-2011)

M.S, Applied Chemistry, Dalian University of Technology (2005-2008)

B.S, Chemical Analysis, Wuhan Insititute of Technology (2001-2005)

 

Research Projects:

2018-2021  Natural Science Foundation of China (21776139)

2016-2019  Natural Science Foundation of Jiangsu Province (BK20161553)

2016-2018  Natural Science Foundation of Jiangsu Provincial Colleges and Universities (16KJB150019)

2014-2016  Natural Science Foundation of China (21302099)

2014-2016  Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry

2012-2015  Natural Science Foundation of Jiangsu Province (BK2012449)

2012-2014  Natural Science Foundation of Jiangsu Provincial Colleges and Universities (12KJB150014)

2011-2013  Scientific Research Start-up Foundation of Nanjing Normal University (2011103XGQ0250)

 

Journal Articles

20. Binbin Liu, Fengli Jin, Tianjiao Wang, Xiaorong Yuan, Wei Han*, Wacker-Type Oxidation Using an Iron Catalyst and Ambient Air and Its Application to Late-Stage Oxidation of Complex Molecules, Angew. Chem. Int. Ed. 2017, Accepted manuscript, DOI: 10.1002/anie.201707006.

19. Hongyuan Zhao, Hongyan Du, Xiaorong Yuan, Tianjiao Wang, Wei Han*, Iron-catalyzed carbonylation of aryl halides with arylborons using stoichiometric chloroform as the carbon monoxide source, Green Chem. 2016, 18, 5782–5787.

18. Hongyuan Zhao, Wei Han*, Ligand-free palladium-catalyzed oxidative carbonylative homocoupling of arylboron reagents at ambient pressure, Eur. J. Org. Chem. 2016, 4279–4283.

17. Wei Han*, Fengli Jin, Qian Zhao, Hongyan Du, Lifang Yao, Acid-free silver-catalyzed cross-dehydrogenative carbamoylation of pyridines with formamides, Synlett 2016, 27, 1854–1859.

16. F. L. Jin, Y. Z. Zhong, X. Zhang, H. C. Zhang, Q. Zhao, W. Han*, Transition metal-free, iodide-mediated domino carbonylation–benzylation of benzyl chlorides with arylboronic acids under ambient pressure of carbon monoxide, Green Chem. 2016, 18, 2598-2603. (Inside cover)

15. F. L. Jin, W. Han*, Transition-metal-free, ambient-pressure carbonylative cross-coupling reactions of aryl halides with potassium aryltrifluoroborates, Chem. Commun. 2015, 51, 9133-9136.

14. H. Y. Du, Q. Ruan, M. H. Qi, W. Han*, Ligand-free Pd-catalyzed double carbonylation of aryl iodides with amines to α‑ketoamides under atmospheric pressure of carbon monoxide and at room temperature, J. Org. Chem. 2015, 80, 7816-7823.

13. W. Han*, F. L. Jin, Q. Zhou, Ligand-_free palladium-_catalyzed hydroxycarbonylation of aryl halides under ambient conditions: Synthesis of aromatic carboxylic acids and aromatic esters, Synthesis-Stuttgart, 2015, 47, 1861-1868.

12. Y. Z. Zhong, W. Han*, Iron-catalyzed carbonylative Suzuki reactions under atmospheric pressure of carbon monoxide, Chem. Commun. 2014, 50, 3874-3877.

11. Q. Zhou, S. H. Wei, W. Han*, In situ generation of palladium nanoparticles: ligand-free palladium catalyzed pivalic acid-assisted carbonylative Suzuki reaction at ambient conditions, J. Org. Chem. 2014, 79, 1454-1460. (Highlighted in “SynFacts”).

10. L. J. Cheng, Y. Z. Zhong, Z. C. Ni, H. Y. Du, F. L. Jin, Q. Rong, W. Han*, Copper-catalyzed carbonylative Suzuki coupling of aryl iodides with arylboronic acids under ambient pressure of carbon monoxide, RSC Adv. 2014, 4, 44312-44316.

9. Y. Z. Zhong, L. X. Yuan, Z. Huang, W. C. Gu, Y. Shao, W. Han*, In situ generated nickel nanoparticle-catalyzed carbonylative Suzuki reactions of aryl iodides with arylboronic acids at ambient CO pressure in poly(ethylene glycol), RSC Adv. 2014, 4, 63216-63220.

8. Y. Z. Zhong, L. X. Yuan, Z. Huang, W. C. Gu, Y. Shao, W. Han*, Unexpected hydrazine hydrate-mediated aerobic oxidation of aryl/heteroaryl boronic acids to phenols in ambient air, RSC Adv. 2014, 4, 33164-33167.

7. L. F. Yao, Q. Zhou, W. Han*, S. H. Wei, Copper powder-catalyzed direct ring-opening arylation of benzazoles with aryl iodides in polyethylene glycol, Eur. J. Org. Chem. 2012, 6856-6860.

6. W. Han, P. Mayer, A. R. Ofial, Palladium-catalyzed dehydrogenative cross couplings of benzazoles with azoles, Angew. Chem. Int. Ed. 2011, 50, 2178-2182. (Selected as a “Hot Paper”; Highlighted in “Synfacts”; commented by F. Glorius et al. Angew. Chem. Int. Ed. 2011, 50, 7479-7481).

5. W. Han, P. Mayer, A. R. Ofial, Palladium-catalyzed direct arylations of azoles with aryl silicon and tin reagents, Chem. Eur. J. 2011, 17, 6904-6908.

4. Wei Han, A. R. Ofial, No detours: palladium-catalyzed oxidative C-H/C-H cross-couplings of heteroarenes, Synlett, 2011, 14, 1951-1955.

3. W. Han, P. Mayer, A. R. Ofial, Iron-catalyzed oxidative mono- and bis-phosphonation of N,N-dialkylanilines, Adv. Synth. Catal. 2010, 352, 1667-1676.

2. W. Han, A. R. Ofial, Iron catalyzed oxidative cyanation of tertiary amines, Chem. Commun. 2009, 40, 5024-5026. (Highlighted in “Synfacts”).

1. W. Han, A. R. Ofial, Iron-catalyzed dehydrogenative phosphonation of N,N-dimethyl-anilines, Chem. Commun. 2009, 40, 6023-6025.

 

Books

 

Patents

1.

Wei Han*, L. F. Yao, Method for synthesis of 2-(arylthio)anilines and 2-phenoxyanilines, CN 201210383747.0.

2.

Wei Han*,H. Y. Du,Q. Ruan,Method for synthesis of α‑ketoamides via catalytic carbonylation, CN 201510246136.5.

3.

Wei Han*, F. L. Jin, Method for synthesis of biarylketones via transition-metal-free carbonylative cross-coupling reactions, CN 201510246960.0.

4.

Wei Han*, L. J. Cheng, Q. Rong, Method for synthesis of biarylketones via copper-catalyzed carbonylation, CN 201410201156.6.

5.

Wei Han*, X. X. Gong, Z. C. Ni, H. Y. Wang, J. L. Fu,Method for synthesis of biarylketones via Ni-catalyzed carbonylationat ambient pressure, CN 201410201223.4.

 

Honors and Awards:

"Qinglan Project" of the Young and Middle-aged Academic Leader of Nanjing Normal University

Academic Title:

Member of the Chinese Chemical Society

Contact: hanwei@njnu.edu.cn; whhanwei@gmail.com