On January 23, 2026, at 10:30 am, the 109th session of the "Chen Bangjie Lecture" hosted by the School of Life Sciences was successfully held in the round conference room on the third floor of Xingzhi Building. At the invitation of Professor Yang Zhou from the School of Life Sciences at Nanjing Normal University, Dr. Jin-Sol Lee from Sungkyunkwan University in South Korea delivered an academic report titled "Toxic effects of triclosan in freshwater water flea Daphnia magna and methods for confirming toxicity via signaling pathways in aquatic invertebrates". The lecture was chaired by Professor Yang Zhou from the School of Life Sciences, and both faculty and students from the school actively participated.

In this lecture presentation, Dr. Jin-Sol Lee started with the water environmental risks of triclosan (TCS), a common antimicrobial agent, and introduced its potential ecological impacts on the freshwater model organism Daphnia magna under complex pollution scenarios. In the mechanism analysis section, the presentation followed a logical chain of "exogenous substance entry and transport - cellular stress response - signaling pathway regulation", combining transport-related processes and changes in key pathways, to propose that complex exposure may enhance the toxic response of Daphnia magna by affecting its internal chemical load and cellular stress pathways. Additionally, the presentation emphasized the strategy of using CRISPR/Cas9 gene editing to construct targeted mutants of key genes (such as p53) in Daphnia magna, and validated the pathway effects through a "wild-type to mutant" comparative experiment, thereby connecting pathway changes at the molecular level more closely with individual phenotypic outcomes.

After the lecture, the participating teachers and students enthusiastically asked questions about the content of Dr. Jin-Sol Lee's presentation. Dr. Jin-Sol Lee provided detailed answers to each question based on her own research experience, creating a lively atmosphere of on-site exchange. This presentation not only demonstrated the analytical framework for complex pollution toxicology research but also provided a clear path for causal verification using gene editing models. It not only presented the overall approach to complex pollution toxicology research but also offered a reference example for future mechanism verification and causal testing using CRISPR/Cas9 in aquatic invertebrates.