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Academic report: Cigarette smoke and lung/lung vascular endothelial cell injury

On July 8-11, 2017, Dr. Qing Lu, associate professor of Brown University Medical School, at the invitation of Prof. Long Chen from Biochemistry and Biological Product Institute of Nanjing Normal University College of Life Sciences, came to our college for academic exchange. Dr. Lu gave a talk entitled “Cigarette smoke and lung/lung vascular endothelial cell injury” at 10:00 am on July 10, and had a lively discussion with teachers, graduate students and undergraduate students from our college on acute lung injury treatment.

Dr. Lu introduced the pathogenesis, hazards and current research progress of acute lung injury, described the effect of adenosine on acute lung injury and explained the mechanism of cigarette smoke-induced acute lung injury. Her studies showed that cigarette smoke-induced reactive oxygen species activated HDAC6 via inhibiting Akt/GSK3β pathway, leading to acute lung injury. In the report, Dr. Lu had in-depth academic exchanges with the attending teachers and students on related issues and let them benefited greatly. After the report, Dr. Lu also conducted deeply exchanges for a possible relative cooperation with the leaders from college and institutes, as well as Prof. Long Chen’s group in the future.

Dr. Qing Lu is an Associate Professor of Medicine and Adviser/Mentor for Ph.D graduate students and postdoc fellows at Medical School of Brown University. She obtained her Ph.D in Physiology & Cell Biology from the Chinese Academy of Sciences and did her postdoc training in Biochemistry & Molecular Biology at University of Michigan (1999-2002) and Brown University (2002-2003) and then became a faculty member of Brown University in 2003. Dr. Lu’s research focuses on lung endothelial cell biology and pathogenesis of lung diseases associated with cigarette smoke. As a Principal Investigator, she is in charge of a total of over 3 million dollars of research funded by National Institutes of Health (NIH), Department of Veterans Affairs (VA), several prestigious research foundations, and Brown University. She has published over 40 peer-reviewed articles, including Circ Res, Autophagy, J Biol Chem、Am J Respir Cell Mol Biol, Am J Physiol Lung Cell Mol Physiol, J Appl Physiol, Microvasc Res, etc. She has also published many highly influential reviews and book chapters and been frequently invited to speak at national and international stages. She services as an Academy Editor for the PLOS One and Grant Reviewer/Study Section member for American Thoracic Society, American Heart Association, Department of Defense, NIH, the Medical Research Council of United Kingdom and National Priorities Program of Qutar National Research Fund.