Dr. Shile Huang, associate professor of Louisiana State University Feist-Weiller Cancer Center, at the invitation of School of Life Sciences and Jiangsu Key Laboratory for Molecular and Medical Biotechnology, came to our college for academic exchange on May 23, 2018. Prof. Huang gave a talk entitled “Preclinical evaluation of SKLB188 as an EGFR inhibitor for head and neck cancer” at the round meeting room on the 3rd floor of School of Life Sciences at 10:00 a.m. The report was chaired by Prof. Long Chen from the Institute of Biochemistry and Biological Products.
In the report, Prof. Huang described the latest research in his Lab and found a new type of EGFR inhibitor, SKLB188, targeting the mutation of EGFR, which can induce apoptosis of cancer cell by regulating MAPK and mTOR signaling pathways. Prof. Huang reported the findings on how the EGFR inhibitor SKLB188 exerts its anti-cancer effect and its molecular mechanism, which provides new ideas for the development of new anticancer drugs in clinical practice. At the end of the seminar, Prof. Huang answered questions and had in-depth academic exchanges with the attending teachers and students on related issues and let them benefited greatly. In the afternoon, Prof. Huang also conducted deeply exchanges for a possible relative cooperation with the leaders from college and institutes, as well as Prof. Long Chen’s group in the future.