On the morning of April 13th, Professor Peter D. Nagy, Department of Plant Pathology in the University of Kentucky, visited College of Life Sciences in NNU. Prof. Nagy gave a seminar entitled 'Insights into the assembly of the tombusvirus replicase: the role of co-opted host proteins and lipids'. He introduced the systemic biology approach from his lab to investigate molecular and cellular mechanism of positive-strand RNA virus replication in hosts. He explained how host proteins as well as lipid molecules are hijacked by viruses to make viral replication factories. Prof. Nagy answered many questions raised by the audience. He also visited several faculty members of the Institute of Microbiology and Bio-technology after his seminar.
Prof. Nagy is a world authority on plant virus replication and recombination. His lab developed a novel and powerful yeast based system to study replication of Tomato bushy stunt virus, a positive strand RNA virus. By using genomics, proteomics, transcriptomics, lipidomics and in vitro biochemistry approaches, his lab discovered many pro-viral and anti-viral host factors, including host proteins and lipids. His work were published on prestigious journals, such as Nature Review Microbiology, PNAS, EMBO J, PLOS Biology, PLOS Pathogens, Annual Review of Phytopathology et al. Prof. Nagy is funded by many funding agencies, including NSF, NIH and USDA. He is section editor for PLOS Pathogens, and is also on editorial boards of several scientific journals including PLANT CELL, Journal of Virology and Virology.