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Shuanglin Chen Professor

Research Interests: 
  • Fungal systematics, diversity and ecology
  • Bioactivity research and development of natural products from fungi and bacteria

Educational background

Postdoctoral fellow, Institute of Microbiology, Chinese Academy of Sciences (Aug. 1997-Dec. 1999)

Ph.D., Phytopathology, Shenyang Agricultural University, China (1997)

MA, Phytopathology, Jilin Agricultural University, China (1990)

BA, Plant Protection, Jilin Agricultural University, China (1984)

Research Projects

  • National Natural Science Foundation of China: Taxonomic studies on the order Liceales of Myxomycetes from China (32070007, 2021.01-2024.12)
  • National Natural Science Foundation of China: Studies on species diversity of myxomycetes in key mountainous areas of Central China (31470143, 2015.01-2018.12)
  • National Natural Science Foundation of China: Studies on taxonomy and species diversity of myxomycetes in forests of tropical China (31170014, 2012.01-2015.12)
  • National Key Technology Research and Development Program of the Ministry of Science and Technology of China: Key technique of high value utilization of Shiraia bambusicola and product development (No.2012BAD36B0502, 2012.01-2015.12)
  • National Science and Technology Basic Work Priorities Program of the Ministry of Science and Technology of China: Flora Fungorum Sinicorum, Clavariaceae and Ramariaceae (2013FY110400, 2013.06-2018.05)
  • Jiangsu Provincial Prospective Research Project of Joint Innovation of Industry, University and Institute: Enzymatic method and technique for converting dairy farm liquid waste into liquid fertilizer (BY2012002, 2012.07-2014.12)
  • Key Program of Natural Science of Jiangsu Higher Education Institutions of China: Studies on species diversity of myxomycetes form Yangtze River Delta regions of China (12KJA180004, 2012.08-2015.12)

Journal Articles (2015-2020)

    Guo LY, Yan SZ, Tao X, Yang Q, Li Q, Wang TS, Yu SQ, Chen SL, 2020. Evaluation of hypocrellin A-loaded lipase sensitive polymer micelles for intervening methicillin-resistant Staphylococcus aureus antibiotic-resistant bacterial infection. Materials Science & Engineering C, 106: 110230, DOI: 10.1016/j.msec.2019.110230
•    Guo LF, Niu SB, Chen SL, Liu L, 2020. Diaporone A, a new antibacterial secondary metabolite from the plant endophytic fungus Diaporthe sp. Journal of Antibiotics, 73: 116-119, DOI: 10.1038/s41429-019-0251-3
•    Zhao N, Li D, Guo BJ, Tao X, Lin X, Yan SZ, Chen SL, 2020. Genome sequencing and analysis of the hypocrellin-producing fungus Shiraia bambusicola S4201. Frontiers in Microbiology, 11: 643, DOI: 10.3389/fmicb.2020.00643
•    Wang R, Zhang X, Gao Y, Chen SL, Yan SZ, 2020. An investigation of macro-ascomycete diversity in Xingshan County, Hubei Province. Journal of Ecology and Rural Environment, 36(3): 342-348, DOI: 10.19741/j.issn.1673-4831.2018.0723 (in Chinese)
•    Gao Y, Zhang X, He G, Shchepin ON, Yan SZ, Chen SL, 2019. Influence of forest type on dark-spored myxomycete community in subtropical forest soil, China. Soil Biology and Biochemistry, 2019, 138: 107606, DOI: 10.1016/j.soilbio.2019.107606
•    Hu HJ, Gao Y, Li X, Chen SL, Yan SZ, Tian XJ, 2019. Identification and nematicidal characterization of proteases secreted by endophytic bacteria Bacillus cereus BCM2. Phytopathology, 110(2): 336-344, DOI: 10.1094/PHYTO-05-19-0164-R
•    Li D, Zhao N, Guo BJ, Lin X, Chen SL, Yan SZ, 2019. Genetic overexpression increases production of hypocrellin A in Shiraia bambusicola S4201. Journal of Microbiology, 57(2): 154-162, DOI: 10.1007/s12275-019-8259-8
•    Li X, Hu HJ, Li JY, Wang C, Chen SL, Yan SZ, 2019. Effects of the endophytic bacteria Bacillus cereus BCM2 on tomato root exudates and Meloidogyne incognita infection. Plant Disease, 103(7): 1551-1558, DOI: 10.1094/PDIS-11-18-2016-RE
•    Qi SS, Guo LY, Yan SZ, Lee RJ, Yu SQ, Chen SL, 2019. Hypocrellin A-based photodynamic action induces apoptosis in A549 cells through ROS-mediated mitochondrial signaling pathway. Acta Pharmaceutica Sinica B, 9(2): 279-293
•    Wang XC, Liu TZ, Chen SL, Li Y, Zhuang WY, 2019. A four-locus phylogeny of rib-stiped cupulate species of Helvella (Helvellaceae, Pezizales) with discovery of three new species. MycoKeys, 60: 45–67, 10.3897/mycokeys.60.38186
•    Zhang X, Wang R, Gao Y, Yan SZ, Chen SL, 2019. Composition and ecological characteristics of macro-basidiomycetes in Xingshan County of the Three Gorges Reservoir Area. Chinese Journal of Applied and Environmental Biology, 25(5): 1099-1106, DOI: 10.19675/j.cnki.1006-687x.2018.12062 (in Chinese)
•    Gao Y, Yan SZ, Wang GW, Chen SL, 2018. Two new species and two new records of myxomycetes from subtropical forests in China. Phytotaxa, 350 (1): 51–63
•    Gao Y, Yan SZ, Wang GW, He G, Chen SL, 2018. Myxomycete diversity and ecology in the Baotianman National Nature Reserve, a subtropical mountain forest in central China. Fungal Ecology, 35: 10-19, DOI: 10.1016/j.funeco.2018.06.002
•    Hu HJ, Wang C, Li X, Tang YY, Wang YF, Chen SL, Yan SZ, 2018. RNA-Seq identification of candidate defense genes targeted by endophytic Bacillus cereus-mediated induced systemic resistance against Meloidogyne incognita in tomato. Pest Management Science, 74(12): 2793-2805, DOI: 10.1002/ps.5066
•    Wang C, Hu HJ, Li X, Wang YF, Tang YY, Chen SL, Yan SZ, 2018. Effects of varying environmental factors on the biological control of Meloidogyne incognita in tomato by Bacillus cereus strain BCM2. Biocontrol Science and Technology, 28(4): 359-376
•    Yu XT, Chen SL, He G, Lin X, Yan SL, 2018. Optimization of liquid culture conditions of mycelium of Ramaria botrytis. Science and Technology of Food Industry, 39(24): 102-108 (in Chinese)
•    Gao Y, Tao W, Yan SZ, Chen SL, 2017. The life cycle of Didymium laxifilum and Physarum album on oat agar culture. Journal of Eukaryotic Microbiology, 64(4): 457-463
•    Guo LY, Yan SZ, Li Q, Xu Q, Lin X, Qi SS, Yu SQ, Chen SL, 2017. Poly(lactic-co-glycolic) acid nanoparticles improve oral bioavailability of hypocrellin A in rat. RSC Advances, 7: 42073-42082, DOI: 10.1039/c7ra04748g
•    Hu HJ, Chen YL, Wang YF, Tang YY, Chen SL, Yan SZ, 2017. Endophytic Bacillus cereus effectively controls Meloidogyne incognita on tomato plants through rapid rhizosphere occupation and repellent action. Plant Disease, 101(3): 448-455
•    Lin X, Yan SZ, Qi SS, Xu Q, Han SS, Guo LY, Zhao N, Chen SL, Yu SQ, 2017. Transferrin-modified nanoparticles enhanced the antitumor efficiency of hypocrellin A by active targeting delivery. Frontiers in Pharmacology, 8: 815
•    Xu Q, Zhang MM, Yan SZ, Cao LF, Li Q, Lin J, Chen SL, 2017. Two dibenzoquinones from the fungus Acremonium cavaraeanum. Natural Product Communications, 12(11):1765-1768
•    Wang GW, Yan SZ, Xu MQ, Dai Q, Yao HQ, Liu QS, Chen SL, 2017. The myxomycete species in Jiangsu, Zhejiang and Anhui of Eastern China. Mycosystema, 36(4): 454-465, DOI: 10.13346/j.mycosystema.160044 (in Chinese)
•    He G, Chen SL, Yan SZ, 2016. Morphological and molecular evidence for a new species in Clavulina from southwestern China. Mycoscience, 57(4): 255-263
•    He G, Wang PR, Chen SL, Yan SZ, 2016. An unexpected discovery of clavarioid fungi: First record of Lepidostroma asianum in China. Mycoscience, 57(2): 150-155
•    Zhao N, Lin X, Qi SS, Luo ZM, Chen SL, Yan SZ, 2016. De novo transcriptome assembly in Shiraia bambusicola to investigate putative genes involved in the biosynthesis of hypocrellin A. International Journal of Molecular Sciences, 17(3): 311
•    Zhou SL, Wang M, Zhao HG, Huang YH, Lin YY, Tan GH, Chen SL, 2016. Penicilazaphilone C, a new antineoplastic and antibacterial azaphilone from the marine fungus Penicillium sclerotiorum. Archives of Pharmacal Research, 39(12): 1621-1627
•    Tao W, Wang N, Yan SZ, Chen SL, 2016. A comparative study on ontogeny of four physaraceous species in laboratory culture. Mycosystema, 35(2): 138-146 (in Chinese)
•    Wang N, Tao W, Chen SL, Yan SZ, 2016. Colonization trends of endophytic bacteria in cotton and their biological control effect on cotton Verticillium wilt. Journal of Plant Protection, 43(2): 207-214 (in Chinese)
•    Wei B, Yan SZ, Chen SL, 2016. Species composition and diversity of myxomycetes in Dinghu Mountain Natural Reserve. Guihaia, 36(2): 137-144 (in Chinese)
•    Liu QS, Yan SZ, Chen SL, 2015. Further resolving the phylogeny of Myxogastria (Slime Molds) based on COI and SSU rRNA genes. Russian Journal of Genetics, 51(1): 39-45
•    Liu QS, Yan SZ, Chen SL, 2015. Species diversity of myxomycetes associated with different terrestrial ecosystems, substrata (microhabitats), and environmental factors. Mycological Progress, 14(5): 27, DOI: 10.1007/s11557-015-1048-9
•    Qi SS, Fan Y, Gong ZN, Yan SZ, Zhao BT, Chen SL, 2015. Genetic diversity of Shiraia bambusicola from East China assessed using ISSR markers. Biochemical Systematics and Ecology, 59: 239-245, DOI: 10.1016/j.bse.2015.01.007
•    Zhou SL, Yan SZ, Liu QS, Chen SL, 2015. Diversity of endophytic fungi associated with the foliar tissue of a hemi-parasitic plant Macrosolen cochinchinensis. Current Microbiology, 70(1): 58-66, DOI: 10.1007/s00284-014-0680-y
•    Huang Z, Yan SZ, Chen SL, 2015. Optimization on fermentation onditions of Simplicillium obclavatum YX016 for the production of anthraquinones. Food Science and Technology, 40(7): 12-17 (in Chinese)
•    Li Q, Yan SZ, Chen SL, 2015. A phylogenetic study of Physarida based on rDNA ITS sequence. Mycosystema, 34(3): 424-433 (in Chinese)
•    Li Q, Yan SZ, Chen SL, 2015. Comparative analysis of the secondary structure of ITS1-5.8S-ITS2 rRNA in the myxomycete order Physarales. Mycosystema, 34(2): 235-245, DOI: 10.13346/j.mycosystema.130224 (in Chinese)

Chapters in Scholarly Books

Chen SL, 2013. Medicinal Myxomycetes of China. pp. 784-821. In Wu XL et al. Medicinal Fungi of China. Science Press. Beijing. pp. 1-923 (in Chinese)
Li Y, Li HZ, Wang Q, Chen SL, 2008. Flora Fungorum Sinicorum. Myxomycetes I. Physarales, Stemonitales. Science Press. Beijing. pp. 1-204. (in Chinese)
Li Y, Li HZ, Wang Q, Chen SL, 2008. Flora Fungorum Sinicorum. Myxomycetes II. Ceratiomyxales, Echinosteliales, Liceales, Trichiales. Science Press. Beijing. pp. 1-238. (in Chinese)
Chen SL (2005) Myxomycetes. pp.5-11. In Zhuang, W.-Y. (ed.) Fungi of Northwestern China. Mycotaxon Ltd. Ithaca. pp. 1-430


Chen SL, Yan SZ, Zhang MM, 2018. 2,7-dihydroxy-3,6,9-trimethyl-9H-xanthene-1,4,5,8-tetraone and its extraction technique. China, ZL201610631806.X
Chen SL, Zhang MM, Yan SZ, 2018. Acremonium cavaraeanum isolated from Shiraia bambusicola and its application in the production of ergosta-4,6,8(14),22-tetraen-3-one. China, ZL201510601408.9
Chen SL, Huang Z, Yan SZ, 2016. Utilization of producing anthraquinones from a strain of Acremonium cucurbitacearum. China, ZL 201410144833.5
Chen SL, Qi SS, Yan SZ, 2016. Preparation and properties of a kind of water-soluble hypocrellin loaded poly(lactic-co-glycolic acid) nanoparticles. China, ZL 201410198946.3
Chen SL, Zhang L, Yan SZ, 2014. A strain of Shewanella putrefaciens and its application in the treatment of organic waste. China, ZL 201210383497.0
Chen SL, Bao YC, Yan SZ, 2013. Industrial production method of bio-fertilizer inoculation agent to manure for shard. China, ZL201110086725.3
Chen SL, Yan SZ, 2012. A strain of Bacillus subtilis and its application in the treatment of dairy farm liquid waste. China, ZL 201110175202.6
Chen SL, Yan SZ, Jiang LJ, 2011. A production method of compound microbial inoculum. China, ZL 200910029205.1


Li Y, Wang Q, Chen SL, Liu SY, Li HZ, 2007. Systematic Studies on Representative Taxa of Myxomycetes. The second Prize of National Nature Science Award of China (2007-Z-105-2-02-R03)
Chen SL, 1999. The First Award on Taxonomy of Cryptogams Established and Funded by Academician Zeng Chengkui

Academic Title

Vice President of Mycological Society of China, 2011-ff
Associate Editor-in-Chief of Mycosystema, 2009-ff
Editorial Board Member of Biodiversity Science, 2014-ff
Associate Editor-in-Chief of Fungal Research, 2004-ff