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Tingming Liang Associate Professor

Research Interests: 
  • Cell biology, Pathophysiology, Systems biology
  • The regulation of Non-coding RNAs, including microRNAs and lncRNAs, in complex diseases, especially in metabolic diseases.
  • Integrate datasets and study them at systems level using bioinformatics, biostatistics and systems biology methods.

Educational Background

PhD, College of life science, Nanjing Normal University (2006-2011)
BA, School of life science, Xinyang Normal University (1999-2003)

Research Projects

  • The National Natural Science Foundation of China (No. 31401009)
  • The Natural Science Foundation of the Jiangsu Higher Education Institutions (No. 12KJB360001)

Journal Articles

  • Guo, L.*, Liang, T.*, microRNAs and their variants in an RNA world: implications for complex interactions and diverse roles in an RNA regulatory network, Brief Bioinform 2017, doi: 10.1093/bib/bbw124. [Epub ahead of print] (Co-Corresponding author) 

  • Guo, L., Zhang, Q., Ma, X., Wang, J., Liang, T.*,. miRNA and mRNA expression analysis reveals potential sex-biased miRNA expression. 2017, Sci Rep, 7, 39812. (Corresponding author)

  • Liang, T., Yu, J., Liu, C., Guo, L.,*. IsomiR expression patterns in Canonical and Dicer-independent miRNAs, 2017, Mol Med Rep, 15, 1071-1078. 

  •  Zhang, W., Wang, P., Chen, S., Zhang, Z., Liang, T.,* and Liu, C.,*. Rhythmic expression of miR-27 targets the clock gene bmal1 through post-transcriptional regulation in the mouse liver. 2016. FASEB Journal. pii: fj.201500120. [Epub ahead of print] (Corresponding author)

  • Liang, T., Yang, C., Li, P., Liu, C. and Guo, L.,*. Genetic analysis of loop sequences in the let-7 gene family reveal a relationship between loop evolution and multiple isomiRs. 2014. PLoS One 9, e113042.

  • Liang, T., Yu, J., Liu, C. and Guo, L.,*. An exploration of evolution, maturation, expression and function relationships in mir-23 - 27 - 24 cluster. 2014. PLoS One 9, e106223.

  • Liang, T.,* Liu, C. and Ye, Z., Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs. 2013. PLoS One 8, e80774. (Corresponding author)

  • Liang, T., Guo, L. and Liu, C.,*. Genome-wide analysis of mir-548 gene family reveals evolutionary and functional implications. 2012. J Biomed Biotechnol 2012, 679563. 

  • Liang, T., Ji, H., Du, J., Ou, J., Li, W., Wu, T., Meng, Q., Gu, W. and Wang, W.,*. Primary culture of hemocytes from Eriocheir sinensis and their immune effects to the novel crustacean pathogen Spiroplasma eriocheiris. 2012. Mol Biol Rep 39, 9747-9754. (IF:1.958)

  • Liang, T., Wu, T., Du, J., Ji, H., Li, Y., Gu, W. and Wang, W., Characterization of a tailless white spot syndrome virus from diseased Penaeus vannamei and Procambarus clarkii in China. 2011. Afr J Biotechnol 10, 13936-13942.

  • Liang, T., Li, X., Du, J., Yao, W., Sun, G., & Dong, X., et al. Identification and isolation of a spiroplasma pathogen from diseased freshwater prawns, macrobrachium rosenbergii , in china: a new freshwater crustacean host. 2011.Aquaculture, 318, 1, 1–6. 

  • Liang, T., Ji, H., Lian, L., Wu, T., Gu, W., & Wang, W. A rapid assay for simultaneous detection of spiroplasma eriocheiris and white spot syndrome virus in procambarus clarkii by multiplex pcr. 2010. Letters in Applied Microbiology, 51, 5, 532–538.

  • Liang, T., Qi Feng, Ting Wu, Wei Gu, Wen Wang*. Use of oxytetracycline for the treatment of tremor disease in the Chinese mitten crab (Eriocheir sinensis). 2009. Disease of Aquatic Orgnisms 84:243-250.