Skip to content Skip to navigation

Faculty

Yuyu Yang Associate Professor

Research Interests: 
The goal of my laboratory is to understand epigenetic regulatory mechanism in cardiovascular diseases and cancer.
Bio: 

Educational Background

PhD, Department of Pathophysiology, Nanjing Medical University (2014)

BS, College of Life Sciences, Southwest University (2009)

Research Projects

National Natural Science Foundation of China (Grant No.: 81870326 & 81503067) 

Natural Science Foundation of Jiangsu Province (Grant No. : BK20150695)

Six talent peaks project in Jiangsu Province (Grant No.: SWYY-102)

Journal Articles

1. Yuyu Yang#, Dewei Chen#, Zhibin Yuan#, Fei Fang, Xian Cheng, Jun Xia, Mingming Fang, Yong Xu*, Yuqi Gao*. Megakaryocytic leukemia 1 (MKL1) ties the epigenetic machinery to hypoxia- induced transactivation of endothelin-1. Nucleic Acids Research, 2013; 41(12): 6005-6017. [SCI IF:8.808] TOP

2. Yuyu Yang, Xian Cheng, Wenfang Tian, Bisheng Zhou, Xiaoyan Wu, Huihui Xu, Fei Fang, Mingming Fang, Yong Xu*. MRTF-A steers an epigenetic complex to activate endothelin-induced pro-inflammatory transcription in vascular smooth muscle cells. Nucleic Acids Research, 2014; 42(16): 10460-10472. [SCI IF:9.112] TOP

3. Xian Cheng#, Yuyu Yang#, Zhiwen Fan, Liming Yu, Hui Bai, Bisheng Zhou, Xiaoyan Wu, Huihui Xu, Mingming Fang*, Aiguo Shen, Qi Chen , Yong Xu*. MKL1 potentiates lung cancer cell migration and invasion by epigenetically activating MMP9 transcription. Oncogene, 2015; 34(44):5570-81. [SCI IF:7.932] TOP

4. Dewei Chen#, Yuyu Yang#, Xian Cheng, Fei Fang, Gang Xu, Zhibin Yuan, Jun Xia, Hui Kong,Weiping Xie, Hong Wang, Mingming Fang, Yuqi Gao*, Yong Xu*. Megakaryocytic Leukemia 1 Directs a Histone H3 Lysine 4 Methyltransferase Complex to Regulate Hypoxic Pulmonary Hypertension. Hypertension, 2015; 65(4): 821-33. [SCI IF:6.294]

5. Yuyu Yang#, Xueyan Li#, Liying Peng, Lin An, Ningyuan Sun, Xuewen Hu, Ping Zhou, Yong Xu, Ping Li*, Jun Chen*. Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway. Biochimica et Biophysica Acta-Molecular Basis of Disease. 2018; 1864(3):882-890. [SCI IF: 4.328] TOP

Contact

Email: yuyujq0818@163.com

Address: College of Life Sciences, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023
Jiangsu, P.R.China.